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Acquired Digital Fibrokeratoma (ADFK): Acral Fibrokeratoma…

In 1968 Bart, et al described 10 cases of an acquired growth that was located on the fingers.  Alothough clinically these lesions resembled a cutaneous horn or a rudimentary digit, they had distinct histologic features.  He suggested the name Acquired Digital Fibrokeratoma (ADFK).  Subsequently Pinkus described 28 more cases but some of these patients had… Read more »

Alopecia Areata: Autoimmune Alopecia…

The first use of the term “Alopecia Areata” is attributed to the Polish physician John Jonston (1603-1675) in his book “Medicina Practica” published in 1664.  For more historical information on Alopecia Areata (AA) click HERE.  Alopecia areata is also referred to as Autoimmune Alopecia.  AA is characterized by rapid and complete hair loss in one… Read more »

Hereditary Hemorrhagic Telangiectasia: Osler-Weber-Rendu…

Hereditary Hemorrhagic Telangiectasia (HHT) was first described by Wiliam Osler, Frederick Parkes Weber and Henri Jules Louis Marie Rendu in the 19th and early 20th century.  It is a rare autosomal dominantly inherited disorder with an estimated prevalence of 1 in 5000 to 1 in 10,000 births worldwide.  It affects blood vessels throughout the body… Read more »

Pyogenic Granuloma: Lobular Capillary Hemangioma…

Pyogenic granuloma (PG) is a relatively common small, eruptive, usually solitary sessile or pedunculated, often friable papule.  Another description is they present as a shiny raspberry-like or “minced meat” surface (see pictures below) papule.  It is also referred to as a lobular capillary hemangioma and granuloma telangiectaticum.  PGs bleed easily on the slightest of trauma… Read more »

Hypoanesthetic Halos In Hawaii: Invasion of the Thrips…

And now for something completely different…  When I was at Tripler Army Medical Center I saw a number of patients present with Hypoanesthetic Halos in Hawaii, also referred to as Thysanoptera dermatitis.  It is a very unique presentation.  It is believed to be caused by Thrips which are small winged insects in the order Thysanoptera… Read more »

Shingles: The Varicella-Zoster Connection…

Shingles, also known as Zoster, is caused by the reactivation of the varicella-zoster virus.  It is a herpes virus.  Following a primary infection with chickenpox (varicella) the virus settles in nerve ganglia and waits to express and raise trouble.  The risk of shingles increases with age and often is related to ganglion compression or injury… Read more »

Vitiligo: Leukoderma, Sins Against the Sun…

Vitiligo is an acquired pigmentary anomaly of the skin manifested by depigmented milky white patches surrounded by a normal or a hyperpigmented border.  It is an ancient disorder, first described in 1550 B.C….the Ebers Papyrus mentioned two forms of depigmentation that could be interpreted as leprosy or depigmentation resembling vitiligo.  In 200 B.C. the Indian… Read more »

Neurofibromatosis 1: Von Recklinghausen’s Disease…

Neurofibromatosis 1 (NF1) is also known as Von Recklinghausen’s Disease.   The neurofibromas of NF1 were first described by Smith in 1849 but Frederick von Recklinghausen was credited with the discovery and coined the name for the disorder in 1882.  NF1 includes more than 85% of all cases of neurofibromatosis.  NF2 is referred to as central or… Read more »

Proteus Syndrome: God of Shapeshifting…

Proteus Syndrome is also known as Elattoproteus Syndrome and elephant man disease.  It may be confused with Neurofibromatosis and the Elephant Man, Joseph Merrick, originally believed to have neurofibromatosis, is now believed to have had Proteus Syndrome.  To see images of Joseph Merrick click HERE.  In 1983 a German pediatrician named the syndrome after the… Read more »