Fixed drug eruptions are common and manifest as edematous plaques in the same sites within 30 minutes to 8 hours of ingestion of the offending medication.  Frequently these medications are taken intermittently and include non-steroidal anti-inflammatory drugs (pyrazolone derivatives, paracetamol, naproxen, oxicams and mefenamic acid), sulfonamides, and trimethoprim are frequent offenders.  Additional agents include barbiturates,… Read more »